In order to evaluate molecular indices of drought tolerance and selection of drought tolerance genotypes in bread wheat a randomized complete block design was carried out with three replications in the field of research station of Sararood, Kermanshah, Iran. Positive significant correlation coefficient was observed between grain yield and proline, soluble sugar and total protein under rainfed condition. Based on the grain yield, proline content, soluble sugar and total protein the genotypes were classified into four clusters using cluster analysis and UPGMA method. Genotypes numbers 4, 9, 10, 11, 18 and 19 in the first clusters indicated the highest performance.