[The isolation and characteristics of continuous virus-producing lymphoid suspension cultures of African green monkey cells]

Vopr Virusol. 1991 Mar-Apr;36(2):130-3.
[Article in Russian]

Abstract

Five continuous lymphoid suspension cell cultures were established by cultivation of lymphocytes from African green monkeys. The immunological typing revealed the mixed pattern of cultures consisting of B and T cell types. Two types of viruses: herpesvirus and retrovirus C-type were demonstrated by electron microscopy. Indirect immunofluorescence and molecular hybridization studies showed one of the viruses to be an EBV-related herpesvirus of green monkeys designated HVGM and the other to belong to H (S) TLV-1 group.

MeSH terms

  • Animals
  • Antibodies, Monoclonal
  • Cell Separation
  • Cells, Cultured / microbiology
  • Cells, Cultured / ultrastructure
  • Chlorocebus aethiops / microbiology*
  • DNA / genetics
  • DNA, Viral / genetics
  • Fluorescent Antibody Technique
  • Herpesviridae / genetics
  • Herpesviridae / isolation & purification*
  • Herpesviridae / ultrastructure
  • Human T-lymphotropic virus 1 / genetics
  • Human T-lymphotropic virus 1 / isolation & purification*
  • Human T-lymphotropic virus 1 / ultrastructure
  • Lymphocytes / microbiology*
  • Lymphocytes / ultrastructure
  • Microscopy, Electron
  • Nucleic Acid Hybridization
  • Virion / genetics
  • Virion / isolation & purification
  • Virion / ultrastructure
  • Virus Cultivation

Substances

  • Antibodies, Monoclonal
  • DNA, Viral
  • DNA