1. Insulin resistance is associated with hepatitis C virus infection and plays a role in the progression of hepatitis C virus-related liver disease and fibrosis. 2. Treating insulin resistance and achieving glycemic control will be important for improving post-liver transplant morbidity and mortality: control of the hepatitis C virus will help to accomplish this. 3. The main renal complication of hepatitis C virus is membranoproliferative glomerulonephritis, and this occurs most commonly in the setting of mixed cryoglobulinemia.