Efficacy of deoxyspergualine for antibody-mediated rejection and proteinuria after kidney transplantation

Ther Clin Risk Manag. 2008 Jun;4(3):641-4. doi: 10.2147/tcrm.s2499.

Abstract

A patient showing antibody-mediated rejection (AMR) with severe vasculitis, and massive proteinuria after kidney transplantation was treated with deoxyspergualine (DSG, Spanidin((R)), Nippon Kayaku). DSG showed marked efficacy for this patient's symptoms. We report on a patient for whom DSG was effective against AMR after renal transplantation.

Keywords: antihuman leukocyte antigen (HLA) antibody; deoxyspergualine (DSG); vascular rejection.

Publication types

  • Case Reports