Drug-eluting stents in the management of peripheral arterial disease

Vasc Health Risk Manag. 2008;4(3):553-9. doi: 10.2147/vhrm.s1712.

Abstract

Since major meta-analyses of randomized controlled trials in interventional cardiology showed the potential of drug-eluting stents in decreasing restenosis and reintervention rates after coronary artery stenting, one of the next steps in the treatment of arterial occlusive disease is the transfer of the active coating technology towards peripheral arterial interventions. In this manuscript, we aim to provide a literature overview on available peripheral (lower limb, renal, and supra-aortic) drug-eluting stent applications, debate the cost implications, and give recommendations for future treatment strategies.

Keywords: below the knee; critical limb ischemia; crural; drug-eluting stent; infrapopliteal; limb salvage.

Publication types

  • Review

MeSH terms

  • Arterial Occlusive Diseases / pathology
  • Arterial Occlusive Diseases / therapy
  • Carotid Stenosis / therapy
  • Constriction, Pathologic
  • Drug-Eluting Stents*
  • Femoral Artery / pathology
  • Humans
  • Peripheral Vascular Diseases / pathology
  • Peripheral Vascular Diseases / therapy*
  • Popliteal Artery / pathology
  • Randomized Controlled Trials as Topic
  • Renal Artery / pathology
  • Secondary Prevention