Drug interactions and pharmacogenomics in the treatment of breast cancer and depression

Am J Psychiatry. 2008 Oct;165(10):1251-5. doi: 10.1176/appi.ajp.2008.08040482.
No abstract available

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenergic Uptake Inhibitors / adverse effects
  • Adrenergic Uptake Inhibitors / pharmacokinetics
  • Adrenergic Uptake Inhibitors / therapeutic use
  • Antidepressive Agents / adverse effects*
  • Antidepressive Agents / pharmacokinetics
  • Antidepressive Agents / therapeutic use
  • Antineoplastic Agents, Hormonal / adverse effects*
  • Antineoplastic Agents, Hormonal / pharmacokinetics
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Biotransformation / genetics
  • Breast Neoplasms / blood
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / psychology
  • Carcinoma, Ductal, Breast / blood
  • Carcinoma, Ductal, Breast / drug therapy*
  • Carcinoma, Ductal, Breast / psychology
  • Cyclohexanols / adverse effects
  • Cyclohexanols / pharmacokinetics
  • Cyclohexanols / therapeutic use
  • Cytochrome P-450 CYP2D6 / genetics
  • Cytochrome P-450 CYP2D6 Inhibitors
  • Delayed-Action Preparations
  • Depressive Disorder, Major / blood
  • Depressive Disorder, Major / drug therapy*
  • Drug Interactions / genetics
  • Drug Therapy, Combination
  • Female
  • Genotype
  • Hot Flashes / blood
  • Hot Flashes / chemically induced
  • Hot Flashes / drug therapy
  • Hot Flashes / psychology
  • Humans
  • Middle Aged
  • Pharmacogenetics*
  • Selective Serotonin Reuptake Inhibitors / adverse effects
  • Selective Serotonin Reuptake Inhibitors / pharmacokinetics
  • Selective Serotonin Reuptake Inhibitors / therapeutic use
  • Tamoxifen / adverse effects*
  • Tamoxifen / analogs & derivatives
  • Tamoxifen / blood
  • Tamoxifen / pharmacokinetics
  • Tamoxifen / therapeutic use
  • Treatment Outcome
  • Venlafaxine Hydrochloride

Substances

  • Adrenergic Uptake Inhibitors
  • Antidepressive Agents
  • Antineoplastic Agents, Hormonal
  • Cyclohexanols
  • Cytochrome P-450 CYP2D6 Inhibitors
  • Delayed-Action Preparations
  • Serotonin Uptake Inhibitors
  • Tamoxifen
  • 4-hydroxy-N-desmethyltamoxifen
  • Venlafaxine Hydrochloride
  • Cytochrome P-450 CYP2D6