Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes

Chem Commun (Camb). 2008 Oct 21:(39):4780-2. doi: 10.1039/b808374f. Epub 2008 Aug 6.

Abstract

A high yielding, batch mode synthesis of diaryl ethers and sulfides by an S(N)Ar fluoride-mediated process in scCO(2) has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous flow process, with high conversions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Dioxide / chemistry*
  • Chromatography, High Pressure Liquid / methods
  • Chromatography, Supercritical Fluid
  • Ethers / chemical synthesis*
  • Ethers / chemistry
  • Fluorobenzenes / chemistry
  • Molecular Structure
  • Pressure
  • Sulfides / chemical synthesis
  • Sulfides / chemistry

Substances

  • Ethers
  • Fluorobenzenes
  • Sulfides
  • Carbon Dioxide