The human polysaccharide- and protein-specific immune response to Streptococcus pneumoniae is dependent on CD4(+) T lymphocytes, CD14(+) monocytes, and the CD40-CD40 ligand interaction

J Allergy Clin Immunol. 2008 Dec;122(6):1231-3. doi: 10.1016/j.jaci.2008.09.006. Epub 2008 Oct 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Capsules / immunology*
  • Bacterial Proteins / immunology*
  • CD4-Positive T-Lymphocytes / immunology*
  • CD40 Antigens / immunology*
  • CD40 Ligand / immunology*
  • Cell Communication / immunology
  • Humans
  • Lipopolysaccharide Receptors / immunology*
  • Mice
  • Mice, SCID
  • Monocytes / metabolism*
  • Pneumococcal Infections / immunology
  • Polysaccharides, Bacterial / immunology*
  • Streptococcus pneumoniae / immunology*

Substances

  • Bacterial Proteins
  • CD40 Antigens
  • Lipopolysaccharide Receptors
  • Polysaccharides, Bacterial
  • CD40 Ligand