Occurrence of a USA300 vancomycin-intermediate Staphylococcus aureus

Jeffrey C Hageman; Jean Patel; Patrick Franklin; Karen Miscavish; Linda McDougal; David Lonsway; Fazle N Khan

doi:10.1016/j.diagmicrobio.2008.08.005

Occurrence of a USA300 vancomycin-intermediate Staphylococcus aureus

Diagn Microbiol Infect Dis. 2008 Dec;62(4):440-2. doi: 10.1016/j.diagmicrobio.2008.08.005. Epub 2008 Oct 7.

Authors

Jeffrey C Hageman¹, Jean Patel, Patrick Franklin, Karen Miscavish, Linda McDougal, David Lonsway, Fazle N Khan

Affiliation

¹ Centers for Disease Control and Prevention, Atlanta, GA 30033, USA. [email protected]

PMID: 18842378
DOI: 10.1016/j.diagmicrobio.2008.08.005

Abstract

A vancomycin-intermediate Staphylococcus aureus (VISA) isolated from the blood of a 46-year-old patient with endocarditis was determined to be pulsed-field type USA300, daptomycin nonsusceptible, and positive for the Panton-Valentine leukocidin genes. Development of the VISA phenotype does not appear limited to traditional health care strains of S. aureus.

Publication types

Case Reports

MeSH terms

Anti-Bacterial Agents / pharmacology*
Drug Resistance, Bacterial*
Endocarditis, Bacterial / blood
Endocarditis, Bacterial / microbiology
Humans
Male
Middle Aged
Staphylococcal Infections / blood
Staphylococcal Infections / microbiology*
Staphylococcus aureus / classification
Staphylococcus aureus / drug effects*
Vancomycin / pharmacology*

Substances

Anti-Bacterial Agents
Vancomycin