Cardiac and extracardiac abnormalities detected by cardiac magnetic resonance in a post-myocardial infarction cohort

Cardiology. 2009;113(1):1-8. doi: 10.1159/000161233. Epub 2008 Oct 10.

Abstract

Objectives: All patients should undergo formal assessment of ventricular function following acute myocardial infarction (AMI). Cardiac magnetic resonance (CMR) is not widely used as a test before discharge in AMI patients. This study sought to determine the impact of contrast-enhanced CMR (ceCMR) scanning before discharge in addition to standard transthoracic echocardiography (TTE) on patient care following AMI.

Methods: 100 patients admitted with AMI, all of whom had a left ventricular ejection fraction (LVEF) <40% on TTE, underwent ceCMR imaging before discharge. Abnormalities of clinical relevance detected on ceCMR, which influenced patient management, are reported.

Results: Each patient (77% male, mean age 58.9 years, SD 12) underwent TTE and ceCMR at a mean 1.4 (range 0.8-3.2) and 4.2 days (range 2-11), respectively, following admission. ceCMR significantly influenced the management of 24/100 (24%) of the patient cohort, through detection of LV thrombus, right ventricular infarction, intracardiac neoplasia, and a variety of intrathoracic and intra-abdominal pathology. There were no issues regarding safety in this high-risk group of patients.

Conclusion: In a cohort of AMI patients with reduced LVEF, ceCMR scanning before discharge improved the management of 24% of the cohort. ceCMR is a useful and safe adjunct to standard care after AMI.

Trial registration: ClinicalTrials.gov NCT00132093.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cohort Studies
  • Echocardiography
  • Female
  • Heart Atria
  • Heart Neoplasms / diagnosis
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Myocardial Infarction / pathology*
  • Myocardium / pathology*
  • Myxoma / diagnosis
  • Randomized Controlled Trials as Topic
  • Thrombosis / diagnosis
  • Ventricular Dysfunction, Left / pathology*

Associated data

  • ClinicalTrials.gov/NCT00132093