The present review systematically summarizes the existing research that has examined two reaction-time-based interference control paradigms, known as the Eriksen Flanker task and the Simon task, in children with and without ADHD. Twelve studies are included, yielding a combined sample size of 272 children with ADHD (M age 9.28 yrs) and 280 typically developing children (M age 9.38 yrs). As predicted, specific disadvantages were found in the ADHD group in terms of reaction time, percentage of errors, and efficiency of performance on incongruent relative to congruent trials, providing evidence for weaker interference control in this group.