MR is a fundamental step in the diagnostic path of patients with medically refractory partial epilepsy (MRPE) potentially amenable to surgery. The most frequent lesions harboured by these patients are: malformations of cortical development (MCD), mainly focal cortical dysplasias (FCD); epileptogenic tumours, such as dysembryoplastic neuroepithelial tumours (DNT) and gangliogliomas (GG); and mesial temporal sclerosis (MTS).