Overcoming an energy crisis?: an adaptive role of glycogen synthase kinase-3 inhibition in ischemia/reperfusion

Circ Res. 2008 Oct 24;103(9):910-3. doi: 10.1161/01.RES.0000338259.37472.b6.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Adenine Nucleotides / metabolism*
  • Animals
  • Cardiotonic Agents / pharmacology*
  • Energy Metabolism / drug effects*
  • Enzyme Inhibitors / pharmacology*
  • Glycogen Synthase Kinase 3 / antagonists & inhibitors*
  • Glycogen Synthase Kinase 3 / metabolism
  • Glycogen Synthase Kinase 3 beta
  • Humans
  • Kinetics
  • Mitochondria, Heart / drug effects*
  • Mitochondria, Heart / enzymology
  • Mitochondrial ADP, ATP Translocases / metabolism
  • Mitochondrial Membrane Transport Proteins / metabolism
  • Mitochondrial Membranes / drug effects
  • Mitochondrial Membranes / metabolism
  • Mitochondrial Permeability Transition Pore
  • Myocardial Contraction / drug effects
  • Myocardial Reperfusion Injury / enzymology
  • Myocardial Reperfusion Injury / prevention & control*
  • Phosphorylation
  • Proto-Oncogene Proteins c-akt / metabolism
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • Proton-Translocating ATPases / metabolism
  • Ventricular Function, Left / drug effects
  • Voltage-Dependent Anion Channels / drug effects*
  • Voltage-Dependent Anion Channels / metabolism

Substances

  • Adenine Nucleotides
  • Cardiotonic Agents
  • Enzyme Inhibitors
  • Mitochondrial Membrane Transport Proteins
  • Mitochondrial Permeability Transition Pore
  • Proto-Oncogene Proteins c-bcl-2
  • Voltage-Dependent Anion Channels
  • Mitochondrial ADP, ATP Translocases
  • Glycogen Synthase Kinase 3 beta
  • Proto-Oncogene Proteins c-akt
  • Glycogen Synthase Kinase 3
  • Proton-Translocating ATPases

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