Post-Kala-Azar dermal leishmaniasis in an HIV-1-infected woman: recovery after amphotericin B following failure of oral miltefosine

Am J Trop Med Hyg. 2008 Nov;79(5):715-8.

Abstract

We describe a case of post-kala-azar dermal leishmaniasis occurring after diagnosis of visceral leishmaniasis in an HIV-1-infected woman. The skin lesions did not recover after treatment with oral miltefosine at 100 mg/day for five cycles of 28 days but responded to treatment with liposomal amphotericin B.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / drug therapy
  • Administration, Oral
  • Adult
  • Amphotericin B / therapeutic use*
  • Antiparasitic Agents / administration & dosage
  • Antiparasitic Agents / therapeutic use*
  • Female
  • HIV-1
  • Humans
  • Leishmaniasis, Cutaneous / complications*
  • Leishmaniasis, Cutaneous / drug therapy
  • Leishmaniasis, Visceral / complications*
  • Leishmaniasis, Visceral / drug therapy
  • Phosphorylcholine / administration & dosage
  • Phosphorylcholine / analogs & derivatives*
  • Phosphorylcholine / therapeutic use
  • Treatment Outcome

Substances

  • Antiparasitic Agents
  • Phosphorylcholine
  • miltefosine
  • Amphotericin B