Hypereosinophilic syndrome in two cats

J Vet Med Sci. 2008 Oct;70(10):1085-9. doi: 10.1292/jvms.70.1085.

Abstract

Two cats showing chronic vomiting, diarrhea and weight loss were found to have leukocytosis with marked eosinophilia. Both cats were diagnosed with hypereosinophilic syndrome by the findings of increased eosinophils and their precursors in the bone marrow, eosinophilic infiltration into multiple organs, and exclusion of other causes for eosinophilia. Although cytoreductive chemotherapy with hydroxycarbamide and prednisolone was performed, these two cats died 48 days and 91 days after the initial presentation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / therapeutic use
  • Blood Cell Count / veterinary
  • Cat Diseases / blood
  • Cat Diseases / diagnosis*
  • Cat Diseases / drug therapy
  • Cats
  • Fatal Outcome
  • Female
  • Hematocrit / veterinary
  • Histocytochemistry / veterinary
  • Hydroxyurea / therapeutic use
  • Hypereosinophilic Syndrome / blood
  • Hypereosinophilic Syndrome / diagnosis
  • Hypereosinophilic Syndrome / drug therapy
  • Hypereosinophilic Syndrome / veterinary*
  • Male
  • Prednisolone / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Prednisolone
  • Hydroxyurea