Initial experience with the Mesh catheter for pulmonary vein isolation in patients with paroxysmal atrial fibrillation

Heart Rhythm. 2008 Nov;5(11):1510-6. doi: 10.1016/j.hrthm.2008.08.024. Epub 2008 Aug 28.

Abstract

Background: A novel catheter design (HD Mesh ablator, Bard) combining high-density circumferential mapping and direct radiofrequency (RF) energy delivery has been developed to map and isolate the pulmonary veins (PVs).

Objective: The purpose of this study was to assess the feasibility of the Mesh catheter for PV isolation in patients with paroxysmal atrial fibrillation (AF).

Methods: Twenty consecutive patients (mean age 56.4 +/- 12.2 years; 16 men) with paroxysmal drug-refractory AF were referred for ablation. The procedure was performed in a stepwise manner: PV isolation was initially attempted with the Mesh ablator, and if that was not successful, a conventional ablation approach was then used.

Results: A total of 73 PVs including seven veins with left common ostium were targeted. Successful deployment of the Mesh was achieved in all but four veins (94.5%). Using the Mesh catheter for ablation, PV isolation was achieved in 46 (63%) of the 73 PVs. The mean (RF) ablation time required to achieve complete isolation was 12.4 +/- 6.1 minutes per PV. The Mesh-only approach allowed isolation of all veins in eight (40%) patients. In combination with conventional ablation, successful PV isolation was achieved in 71 (97%) of 73 PVs. No complications attributable to the Mesh ablator occurred in this series.

Conclusions: PV isolation using the Mesh catheter is feasible and may simplify the current PV isolation procedures. With the current catheter design, PV isolation could be achieved in 63% of PVs. A larger Mesh diameter with an over-the-wire design may help improve the acute success rate.

MeSH terms

  • Aged
  • Atrial Fibrillation / surgery*
  • Catheter Ablation / instrumentation*
  • Feasibility Studies
  • Female
  • Heart Conduction System / surgery*
  • Humans
  • Male
  • Pulmonary Veins / surgery*
  • Treatment Outcome