Abstract
Polyethylenimine (PEI), an organic branched or linear polyamine polymer, has been successfully used in the past for DNA complexation and transfection in vitro and in vivo into several cell lines and tissues. PEI was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal chemistry. In this brief critical review the uses and applications of this versatile polymeric molecule will be discussed.
MeSH terms
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Anti-Infective Agents / administration & dosage
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / therapeutic use
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Chemistry, Pharmaceutical / methods*
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Chemistry, Pharmaceutical / trends
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Coated Materials, Biocompatible / chemistry
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Drug Delivery Systems / methods
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Molecular Structure
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Nanoparticles / chemistry
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Photochemotherapy / methods
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Polyethyleneimine / administration & dosage
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Polyethyleneimine / chemistry*
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Polyethyleneimine / therapeutic use
Substances
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Anti-Infective Agents
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Coated Materials, Biocompatible
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Polyethyleneimine