Familial membranous glomerulopathy, toxic exposure and/or genetic sensibility?

C Muller; F Alenabi; F Chantrel; S Muller; C Trivin; B Faller

doi:10.5414/cnp70422

Familial membranous glomerulopathy, toxic exposure and/or genetic sensibility?

Clin Nephrol. 2008 Nov;70(5):422-3. doi: 10.5414/cnp70422.

Authors

C Muller¹, F Alenabi, F Chantrel, S Muller, C Trivin, B Faller

Affiliation

¹ Department of Nephrology, Hôpital Civil de Colmar, Avenue Rome, Colmar, France. [email protected]

PMID: 19000543
DOI: 10.5414/cnp70422

Abstract

Membranous nephropathy rarely occurs as a familial disease. We report two siblings (brother and sister) who presented with nephrotic syndrome and many vascular complications. HLA identities and potential toxic exposure may be concurring in these cases.

Publication types

Case Reports

MeSH terms

Adult
Complement Membrane Attack Complex / immunology*
Creatinine / blood
Disease Progression
Female
Follow-Up Studies
Genetic Predisposition to Disease*
Glomerular Filtration Rate / physiology
Glomerulonephritis, Membranous / blood
Glomerulonephritis, Membranous / etiology*
Glomerulonephritis, Membranous / physiopathology
Humans
Immunity, Cellular / immunology*
Male

Substances

Complement Membrane Attack Complex
Creatinine