Molecular cloning and primary structure of squid (Loligo forbesi) rhodopsin, a phospholipase C-directed G-protein-linked receptor

Biochem J. 1991 Feb 15;274 ( Pt 1)(Pt 1):35-40. doi: 10.1042/bj2740035.

Abstract

The sequence of squid (Loligo forbesi) rhodopsin was determined by protein and cDNA sequencing. The protein has close similarity to octopus rhodopsin, having an N-terminal region (residues 1-340) which resembles other guanine-nucleotide-binding protein (G-protein)-linked receptors and a repetitive proline-rich C-terminus (residues 340-452). Comparison of the sequence of squid rhodopsin with those of other members of the G-protein-linked receptor superfamily reveals features which we predict to have both structural and functional importance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular / methods
  • Decapodiformes
  • GTP-Binding Proteins / metabolism
  • Molecular Sequence Data
  • Oligonucleotide Probes
  • Plasmids
  • Protein Conformation
  • Restriction Mapping
  • Rhodopsin / genetics*
  • Rhodopsin / isolation & purification
  • Rhodopsin / metabolism
  • Type C Phospholipases / metabolism

Substances

  • Oligonucleotide Probes
  • Rhodopsin
  • Type C Phospholipases
  • GTP-Binding Proteins

Associated data

  • GENBANK/M64055
  • GENBANK/M64056
  • GENBANK/M64057
  • GENBANK/M64058
  • GENBANK/M64059
  • GENBANK/M64060
  • GENBANK/M83107
  • GENBANK/S67100
  • GENBANK/S78039
  • GENBANK/X56788