Effect of oleamide on pentylenetetrazole-induced seizures in rats

Bull Exp Biol Med. 2008 Feb;145(2):225-7. doi: 10.1007/s10517-008-0056-z.

Abstract

Oleamide exhibits antiepileptic activity and significantly decreases the degree of pentylenetetrazole-induced seizures.

MeSH terms

  • Animals
  • Anticonvulsants / therapeutic use*
  • Hypnotics and Sedatives / therapeutic use*
  • Oleic Acids / therapeutic use*
  • Pentylenetetrazole / adverse effects*
  • Rats
  • Seizures / chemically induced*
  • Seizures / drug therapy*
  • Seizures / mortality

Substances

  • Anticonvulsants
  • Hypnotics and Sedatives
  • Oleic Acids
  • oleylamide
  • Pentylenetetrazole