Abstract
As a step toward a fully automated front-end microfluidic chip for MS proteomics, we propose a system capable of performing online tryptic digest and ESI-MS, using a replaceable on-chip digestion microcolumn based on self-assembled magnetic particles.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Dimethylpolysiloxanes / chemistry
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Magnetics
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Microfluidic Analytical Techniques / instrumentation*
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Microfluidic Analytical Techniques / methods
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Proteins / analysis
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Proteomics / methods
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Spectrometry, Mass, Electrospray Ionization / instrumentation*
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Spectrometry, Mass, Electrospray Ionization / methods
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Trypsin / chemistry*
Substances
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Dimethylpolysiloxanes
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Proteins
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baysilon
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Trypsin