Abstract
Chronic recurrent multifocal osteomyelitis is an unusual inflammatory process of unknown origin involving multiple osseous sites, often recurrently. Selective immunoglobulin M (IgM) deficiency is a rare primary immunodeficiency disease, which can be associated with autoimmune diseases such as systemic lupus erythematosus, Hashimoto's disease, or hemolytic anemia. Here we report a case of a chronic recurrent multifocal osteomyelitis coexisting with selective IgM deficiency.
MeSH terms
-
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
-
Antirheumatic Agents / therapeutic use
-
Arthralgia / immunology
-
Arthralgia / physiopathology
-
Autoimmune Diseases / blood
-
Autoimmune Diseases / immunology*
-
Autoimmune Diseases / physiopathology
-
Biomarkers / analysis
-
Biomarkers / blood
-
Bone and Bones / diagnostic imaging
-
Bone and Bones / immunology*
-
Bone and Bones / pathology
-
Chemotaxis, Leukocyte / immunology
-
Child
-
Chronic Disease / drug therapy
-
Femur / pathology
-
Humans
-
Immunoglobulin M / blood
-
Immunoglobulin M / deficiency*
-
Lymphocytes / pathology
-
Magnetic Resonance Imaging
-
Male
-
Osteomyelitis / blood
-
Osteomyelitis / immunology*
-
Osteomyelitis / physiopathology
-
Pelvis / pathology
-
Plasma Cells / pathology
-
Radionuclide Imaging
-
Recurrence
-
Spine / pathology
-
Sulfasalazine / therapeutic use
-
Treatment Outcome
Substances
-
Anti-Inflammatory Agents, Non-Steroidal
-
Antirheumatic Agents
-
Biomarkers
-
Immunoglobulin M
-
Sulfasalazine