Therapeutic drug monitoring of voriconazole in a child with invasive aspergillosis requiring extracorporeal membrane oxygenation

Ther Drug Monit. 2008 Dec;30(6):643-6. doi: 10.1097/FTD.0b013e3181898b0c.

Abstract

We describe a patient with invasive pulmonary aspergillosis on extracorporeal membrane oxygenation therapy in which therapeutic drug monitoring and individualization of therapy by measuring voriconazole plasma concentrations were performed.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / blood
  • Antifungal Agents / pharmacokinetics
  • Antifungal Agents / therapeutic use
  • Aspergillosis / drug therapy*
  • Child, Preschool
  • Drug Monitoring*
  • Extracorporeal Membrane Oxygenation*
  • Humans
  • Male
  • Pyrimidines / blood
  • Pyrimidines / pharmacokinetics*
  • Pyrimidines / therapeutic use*
  • Triazoles / blood
  • Triazoles / pharmacokinetics*
  • Triazoles / therapeutic use*
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole