Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil

Mem Inst Oswaldo Cruz. 2008 Nov;103(7):734-5. doi: 10.1590/s0074-02762008000700018.

Abstract

The presence of enterotoxigenic Bacteroides fragilis and nontoxigenic B. fragilis (NTBF) among 109 strains isolated from 1980-2008 in Brazil were investigated by PCR. One strain, representing 0.9% of the total analyzed strains, harbored the bft gene which was identified as bft-1 isoform based on PCR-RFLP and sequencing. Forty-nine strains (44.9%) exhibited the NTBF pattern III which possesses the flanking region required for pathogenicity island acquisition in which the bft gene is codified. These data reinforce the potential of B. fragilis as an emerging enteropathogen in our country.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteroides fragilis / classification
  • Bacteroides fragilis / genetics*
  • Bacteroides fragilis / pathogenicity
  • Brazil
  • Enterotoxins / biosynthesis*
  • Genes, Bacterial / genetics*
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length

Substances

  • Enterotoxins