Emergence of abnormal clone with monsomy 7 in Philadelphia negative cells of CML patients treated with tyrosine kinase inhibitors

Int J Hematol. 2009 Jan;89(1):123-125. doi: 10.1007/s12185-008-0224-y. Epub 2008 Dec 18.

Authors

Monika Ribeiro de Mello Conchon^{1

2

3}, Israel Bendit⁴, Patricia Ferreira⁵, Walter Lima⁴, Cristina Kumeda⁵, Lucia Dias⁴, Dalton de Alencar Fischer Chamone⁴, Pedro Enrique Dorlhiac-Llacer⁴

Affiliations

¹ Disciplina de Hematologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil. [email protected].
² Laboratorio de Cytogenetica, Disciplina de Hematologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil. [email protected].
³ Cytogenetic Laboratory, Av. Dr. Eneias de Carvalho Aguiar, 155-1º andar, Cerqueira César, São Paulo, 05403-000, Brazil. [email protected].
⁴ Disciplina de Hematologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
⁵ Laboratorio de Cytogenetica, Disciplina de Hematologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

PMID: 19093165
DOI: 10.1007/s12185-008-0224-y

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Benzamides
Chromosomes, Human, Pair 7*
Clone Cells / pathology
Dasatinib
Humans
Imatinib Mesylate
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / etiology
Male
Middle Aged
Monosomy*
Myelodysplastic Syndromes / diagnosis
Myelodysplastic Syndromes / etiology
Piperazines
Protein Kinase Inhibitors / adverse effects*
Pyrimidines
Thiazoles
Young Adult

Substances

Benzamides
Piperazines
Protein Kinase Inhibitors
Pyrimidines
Thiazoles
Imatinib Mesylate
Dasatinib