Correlation of calcium measurement with low dose 64-slice CT and angiographic stenosis in patients with suspected coronary artery disease

Int J Cardiol. 2010 Apr 15;140(2):249-52. doi: 10.1016/j.ijcard.2008.11.043. Epub 2008 Dec 20.

Abstract

Coronary artery calcium is a sensitive marker of coronary artery disease (CAD). This study was to determine the relationship between coronary calcium score (CCS) and angiographic stenosis on a patient-based or vessel-based analysis. 91 consecutive patients underwent both low dose 64-slice CT calcium scoring scan and conventional angiography of the heart. The total CCS of abnormal coronary angiogram (n=45) was 297.38+/-416.93, whereas that of normal coronary angiogram (n=46) was 5.37+/-9.35 (P<0.001). The CCS and degree of stenosis were moderately correlated on patient-based or vessel-based analysis (r=0.517, 0.521, respectively; both P<0.001). In conclusion, CCS could reflect the degree of vessel stenosis to some extent, but CCS of zero could not rule out CAD.

Publication types

  • Clinical Trial
  • Letter

MeSH terms

  • Aged
  • Calcinosis / diagnostic imaging*
  • Calcinosis / epidemiology
  • Calcinosis / metabolism
  • Calcium / metabolism*
  • Coronary Angiography*
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / metabolism
  • Female
  • Humans
  • Male
  • Middle Aged
  • Reference Standards
  • Risk Factors
  • Tomography, Spiral Computed / methods*
  • Tomography, Spiral Computed / standards

Substances

  • Calcium