Stem cells do play with dice: a statistical physics view of transcription

Cell Cycle. 2009 Jan 1;8(1):43-8. doi: 10.4161/cc.8.1.7216. Epub 2009 Jan 16.

Abstract

Embryonic stem cells display wide-spread pervasive transcriptional output. Here, we propose that multiple simultaneous transcriptional states underlay pluripotency.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Embryonic Stem Cells / metabolism
  • Humans
  • Models, Biological
  • Models, Statistical*
  • Stem Cells / metabolism*
  • Transcription, Genetic*