Acute retinal necrosis in primary herpes simplex virus type I infection

Pediatr Infect Dis J. 2009 Feb;28(2):163-4. doi: 10.1097/INF.0b013e318186258f.

Abstract

Here we report the case of an immunocompetent 8-year-old child who developed acute retinal necrosis concomitant with a primary herpes simplex virus type I infection. Ocular inflammation changed along with the development of a specific antibody titer in the serum. This evidence suggests that the immune response of the host can significantly modulate the clinical aspect of the ocular infection.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Anterior Chamber / pathology
  • Anti-Inflammatory Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Child
  • Fundus Oculi
  • Herpes Simplex / complications*
  • Herpesvirus 1, Human* / genetics
  • Herpesvirus 1, Human* / immunology
  • Herpesvirus 1, Human* / isolation & purification
  • Humans
  • Immunocompetence
  • Male
  • Prednisone / therapeutic use
  • Retina / pathology
  • Retina / virology
  • Retinal Necrosis Syndrome, Acute / complications*
  • Retinal Necrosis Syndrome, Acute / virology*

Substances

  • Anti-Inflammatory Agents
  • Antiviral Agents
  • Prednisone
  • Acyclovir