Clopidogrel in acute coronary syndrome: to genotype or not?

Lancet. 2009 Jan 24;373(9660):276-8. doi: 10.1016/S0140-6736(08)61846-2. Epub 2008 Dec 26.

Author

Robert F Storey¹

Affiliation

¹ Cardiovascular Research Unit, University of Sheffield School of Medicine, Sheffield S10 2RX, UK. R.F.Storey@sheffi eld.ac.uk

PMID: 19108882
DOI: 10.1016/S0140-6736(08)61846-2

No abstract available

Publication types

Comment

MeSH terms

Acute Coronary Syndrome / drug therapy*
Acute Coronary Syndrome / enzymology
Acute Coronary Syndrome / genetics
Adenosine Diphosphate / metabolism
Adenosine Diphosphate / physiology*
Aryl Hydrocarbon Hydroxylases / drug effects
Aryl Hydrocarbon Hydroxylases / metabolism
Clopidogrel
Cytochrome P-450 CYP2C19
Genotype
Humans
Platelet Aggregation Inhibitors / metabolism
Platelet Aggregation Inhibitors / pharmacology
Platelet Aggregation Inhibitors / therapeutic use*
Ticlopidine / analogs & derivatives*
Ticlopidine / metabolism
Ticlopidine / pharmacology
Ticlopidine / therapeutic use

Substances

Platelet Aggregation Inhibitors
Adenosine Diphosphate
Clopidogrel
Aryl Hydrocarbon Hydroxylases
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Ticlopidine