Comparison of 2D digital subtraction angiography and 3D rotational angiography in the evaluation of dome-to-neck ratio

AJNR Am J Neuroradiol. 2009 Apr;30(4):831-4. doi: 10.3174/ajnr.A1444. Epub 2009 Jan 8.

Abstract

Background and purpose: Dome-to-neck ratio of intracranial aneurysms is an important predictor of outcomes of endovascular coiling. 3D imaging techniques are increasingly used in evaluating the dome-to-neck ratio of aneurysms for intervention. The purpose of this study was to determine whether 3D rotational angiography (3DRA) can be used to determine accurately the dome-to-neck ratio of intracranial aneurysms when compared with conventional 2D digital subtraction angiography (2D DSA).

Materials and methods: A retrospective analysis of 180 patients with 205 intracranial aneurysms who underwent both 2D DSA and 3DRA for evaluation of previously untreated aneurysms was conducted. Dome-to-neck ratios were compared between 2D DSA and 3DRA images. The mean difference in dome-to-neck ratios between 2D DSA and 3DRA was calculated. The proportions of "wide-neck" aneurysms seen on 2D DSA and 3DRA were compared by using 2 different definitions of "wide-neck," including <1.5 and <2.0.

Results: The average dome-to-neck ratio was 1.81 +/- 0.55 and 1.55 +/- 0.48 for 2D DSA and 3DRA, respectively (P < .0001). When we defined "wide-neck" as a dome-to-neck ratio <1.5, sixty-nine (33.7%) aneurysms were wide-neck on 2D DSA compared with 119 (58%) on 3DRA (P < .0001). When we defined "wide-neck" as dome-to-neck ratio <2.0, one hundred forty-two (69.3%) aneurysms were wide-neck on 2D DSA compared with 173 (84.4%) on 3DRA (P = .0004).

Conclusions: In this retrospective study, 3DRA measurements resulted in significantly lower dome-to-neck ratios and significantly larger proportions of aneurysms defined as "wide-neck" compared with 2D DSA. Scrutiny of 2D DSA may offer substantial benefit over 3D techniques when triaging patients to or from endovascular therapy.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Angiography, Digital Subtraction*
  • Cerebral Angiography*
  • Cerebral Arteries / diagnostic imaging
  • Cerebral Arteries / pathology
  • Embolization, Therapeutic
  • Female
  • Humans
  • Imaging, Three-Dimensional*
  • Intracranial Aneurysm / diagnostic imaging*
  • Intracranial Aneurysm / pathology*
  • Intracranial Aneurysm / therapy
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Young Adult