Abdominal wall recurrence of Hilar bile duct cancer 12 years after a curative resection: report of a case

Surg Today. 2009;39(1):72-6. doi: 10.1007/s00595-008-3791-x. Epub 2009 Jan 8.

Abstract

A 74-year-old woman was diagnosed with hilar bile duct cancer, and underwent a curative resection of the bile duct and the left and caudate lobes of the liver in 1995. Ten years later (April 2005), she noted a small mass in the abdominal wall. The mass slowly enlarged to reach 4 cm in diameter by January 2007. With a diagnosis of a possible recurrence of bile duct cancer, a laparotomy was thus performed. The abdominal wall tumor was buried in the rectus abdominis muscle and was tightly attached to the ileum. The lesion was resected en bloc with the associated rectus muscle and ileocecal region. A histopathological examination of the resected specimen revealed tubular adenocarcinoma that closely resembled the original primary bile duct cancer. In addition, the immunohistochemical staining pattern of the abdominal tumor was identical to that of the original bile duct cancer. This indicated that the abdominal tumor represented a local recurrence (probably due to peritoneal implantation) at 12 years after the resection of the hilar bile duct cancer. This case emphasizes that long-time surveillance is required for patients with bile duct cancer, even if they have survived without recurrence for more than 5 years after a curative resection.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / diagnostic imaging
  • Abdominal Neoplasms / pathology*
  • Abdominal Neoplasms / surgery
  • Abdominal Wall
  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Aged
  • Bile Duct Neoplasms / pathology*
  • Bile Duct Neoplasms / surgery
  • Bile Ducts / pathology*
  • Bile Ducts / surgery
  • Female
  • Hepatectomy / methods
  • Humans
  • Immunohistochemistry
  • Neoplasms, Second Primary / diagnostic imaging
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / surgery
  • Prognosis
  • Radiography
  • Recurrence
  • Treatment Outcome