On the role of cell signaling models in cancer research

Cancer Res. 2009 Jan 15;69(2):400-2. doi: 10.1158/0008-5472.CAN-08-4422.

Abstract

The main objective of this review is to emphasize the role and importance of the careful mathematical/computational modeling of signaling networks for the understanding of aberrant signaling in cancer and for the development of targeted therapies.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Models, Biological*
  • Neoplasms / metabolism*
  • Neoplasms / pathology
  • Neoplasms / therapy
  • Signal Transduction*