Hepatic veno-occlusive disease and human herpes virus 7 infection in primary agammaglobulinemia

Jason S Soden; Michael R Narkewicz; Joel E Haas; Ronald J Sokol

doi:10.1016/j.jpeds.2008.08.048

Hepatic veno-occlusive disease and human herpes virus 7 infection in primary agammaglobulinemia

J Pediatr. 2009 Feb;154(2):299-302. doi: 10.1016/j.jpeds.2008.08.048.

Authors

Jason S Soden¹, Michael R Narkewicz, Joel E Haas, Ronald J Sokol

Affiliation

¹ Pediatric Liver Center and Liver Transplantation Program, Department of Pediatrics, University of Colorado Denver School of Medicine, and The Children's Hospital, Aurora, CO 80045, USA. [email protected]

PMID: 19150678
DOI: 10.1016/j.jpeds.2008.08.048

Abstract

Hepatobiliary disease has been described in Bruton's x-linked agammaglobulinemia; however, veno-occlusive disease has not been reported in this setting. We report a case of end-stage liver disease in a patient with x-linked agammaglobulinemia who was found to have VOD and evidence of human herpes virus 7 infection in the explanted liver after transplantation.

Publication types

Case Reports

MeSH terms

Adolescent
Agammaglobulinemia / complications*
Agammaglobulinemia / drug therapy
DNA, Viral / blood
Hepatic Veno-Occlusive Disease / complications*
Hepatic Veno-Occlusive Disease / surgery
Herpesvirus 7, Human / genetics
Humans
Immunoglobulins, Intravenous / therapeutic use
Liver / pathology
Liver Failure / etiology*
Liver Transplantation
Male
Roseolovirus Infections / complications
Roseolovirus Infections / diagnosis*

Substances

DNA, Viral
Immunoglobulins, Intravenous