Vidalols A and B, new anti-inflammatory bromophenols from the Caribbean marine red alga Vidalia obtusaloba

Experientia. 1991 Aug 15;47(8):851-3. doi: 10.1007/BF01922471.

Abstract

Chemical studies of the Caribbean red alga Vidalia obtusaloba have resulted in the isolation of two new bromophenolic metabolites, vidalols A and B (1, 2). The new compounds were discovered as part of an organized effort to isolate new naturally-occurring anti-inflammatory agents with a focus upon those which may function through the inhibition of phospholipase A2.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / isolation & purification*
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Bromobenzenes
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Mice
  • Molecular Structure
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Phenols / pharmacology
  • Phloroglucinol
  • Phospholipases A / antagonists & inhibitors
  • Phospholipases A2
  • Rhodophyta / chemistry*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Bromobenzenes
  • Phenols
  • vidalol A
  • vidalol B
  • Phloroglucinol
  • Phospholipases A
  • Phospholipases A2