Tracking temporal evolution of nonlinear dynamics in hippocampus using time-varying volterra kernels

Annu Int Conf IEEE Eng Med Biol Soc. 2008:2008:4996-9. doi: 10.1109/IEMBS.2008.4650336.

Abstract

Hippocampus and other parts of the cortex are not stationary, but change as a function of time and experience. The goal of this study is to apply adaptive modeling techniques to the tracking of multiple-input, multiple-output (MIMO) nonlinear dynamics underlying spike train transformations across brain subregions, e.g. CA3 and CA1 of the hippocampus. A stochastic state point process adaptive filter will be used to track the temporal evolutions of both feedforward and feedback kernels in the natural flow of multiple behavioral events.

MeSH terms

  • Action Potentials / physiology*
  • Algorithms*
  • Computer Simulation
  • Hippocampus / physiology*
  • Humans
  • Models, Neurological*
  • Nerve Net / physiology*
  • Neurons / physiology*
  • Nonlinear Dynamics
  • Synaptic Transmission / physiology*