En bloc paediatric kidney transplant: is this the best use of a scarce resource?

ANZ J Surg. 2009 Jan-Feb;79(1-2):27-32. doi: 10.1111/j.1445-2197.2008.04793.x.

Abstract

Background: Kidney transplants using organs from paediatric cadaver donors are uncommon and technically difficult. It has become accepted practice to transplant both kidneys en bloc from donors of 5 years into a single recipient. We aim to compare outcomes of en bloc kidney (EBK) transplants versus single kidney (SK) transplants from cadaver donors of age 5 years and lesser.

Methods: Data reported to Australia and New Zealand Dialysis and Transplant Registry from 1989 to 2004 were analysed.

Results: From donors 5 years of age and younger, there were 33 EBK and 38 SK transplants carried out. Overall graft survival rates at 1 and 5 years were 78 and 61%, respectively, in the EBK group and 63 and 55%, respectively, in the SK group (P = 0.94). Vascular thrombosis was the most common cause of early graft loss with an incidence of 11 and 18%, respectively, in the EBK and SK groups (P = 0.5).

Conclusion: There is a trend towards a lower vascular thrombosis rate and a better long-term graft survival in EBK transplants. These transplants will remain a technical challenge for the surgeon and EBK transplants should remain the technique of choice for donors of 5 years and lesser.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Child, Preschool
  • Graft Survival
  • Humans
  • Infant
  • Kidney Transplantation / methods*
  • Metabolic Syndrome
  • Middle Aged
  • Tissue Donors