Effective determination of dry weight by intradialytic bioimpedance analysis in hemodialysis

Background: The new dry weight (DW) assessment technique by intradialytic sequential bioimpedance analysis (BIA) was evaluated in this study.

Methods: Intradialytic changes in the ratio of resistance at baseline per each time point (R(0)/R(t)) determined by a total body single-frequency BIA were recorded in 19 hemodialysis patients. The bioimpedance DW (BIADW) could be drawn from a time point at which R(0)/R(t) was constant.

Results: After the first session where the previous DW was prescribed, the participants could be divided into 2 groups: the under BIADW and over BIADW groups. In the under BIADW group, the BIADW was achieved earlier than the previous DW. The intradialytic symptoms disappeared without changes in the home-monitored mean blood pressure and antihypertensive agents at 1-month follow-up. In the over BIADW group, the BIADW could be obtained in the following sessions and the prescribed DW could be gradually reduced. The home-monitored mean blood pressure was decreased and the numbers of antihypertensive drugs were reduced.

Conclusion: Intradialytic single-frequency BIA assessment can be used as a tool to accurately determine the DW.