Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap

Roger S McIntyre; Natalie L Rasgon; David E Kemp; Ha T Nguyen; Candy W Y Law; Valerie H Taylor; Hanna O Woldeyohannes; Mohammad T Alsuwaidan; Joanna K Soczynska; Byungsu Kim; Maria T Lourenco; Linda S Kahn; Benjamin I Goldstein

doi:10.1007/s11892-009-0010-0

Metabolic syndrome and major depressive disorder: co-occurrence and pathophysiologic overlap

Curr Diab Rep. 2009 Feb;9(1):51-9. doi: 10.1007/s11892-009-0010-0.

Authors

Roger S McIntyre¹, Natalie L Rasgon, David E Kemp, Ha T Nguyen, Candy W Y Law, Valerie H Taylor, Hanna O Woldeyohannes, Mohammad T Alsuwaidan, Joanna K Soczynska, Byungsu Kim, Maria T Lourenco, Linda S Kahn, Benjamin I Goldstein

Affiliation

¹ Mood Disorders Psychopharmacology Unit, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada. [email protected]

PMID: 19192425
DOI: 10.1007/s11892-009-0010-0

Abstract

The metabolic syndrome and its components are associated with depressive symptomatology. This article discusses the rate of co-occurrence and the points of pathophysiologic commonality between the metabolic syndrome and major depressive disorder.

Publication types

Review

MeSH terms

Bipolar Disorder / epidemiology
Depressive Disorder / epidemiology*
Depressive Disorder / physiopathology*
Depressive Disorder / psychology
Diseases in Twins
Female
Humans
Metabolic Syndrome / complications
Metabolic Syndrome / epidemiology
Metabolic Syndrome / physiopathology*
Metabolic Syndrome / psychology*
Mood Disorders / epidemiology
Oxidative Stress / physiology
Risk Factors