Seven-year discordance in age at onset in monozygotic twins with inherited prion disease (P102L)

Neuropathol Appl Neurobiol. 2009 Aug;35(4):427-432. doi: 10.1111/j.1365-2990.2009.01012.x. Epub 2009 Jan 21.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age of Onset
  • Brain / metabolism
  • Brain / pathology
  • Creutzfeldt-Jakob Syndrome / metabolism
  • Diseases in Twins / epidemiology*
  • Diseases in Twins / genetics
  • Diseases in Twins / pathology
  • Environment
  • Female
  • Humans
  • Middle Aged
  • Pedigree
  • PrPSc Proteins / metabolism
  • Prion Diseases / epidemiology*
  • Prion Diseases / genetics
  • Prion Diseases / pathology
  • Prion Proteins
  • Prions / genetics
  • Sequence Analysis, DNA
  • Twins, Monozygotic*

Substances

  • PRNP protein, human
  • PrPSc Proteins
  • Prion Proteins
  • Prions