Abstract
A pertussis outbreak primarily affecting school-age children in Ludwigslust, Germany, was investigated in 2006 to estimate attack rates and relative risk of pertussis according to time since last vaccination, after a complete primary course. Results suggested waning immunity beginning approximately 5 years after the last dose of pertussis vaccination. Most cases could have been prevented by earlier booster vaccination.
MeSH terms
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Adolescent
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Adult
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Aged
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Antibodies, Bacterial / blood*
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Bordetella pertussis / immunology*
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Child
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Child, Preschool
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Cohort Studies
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Disease Outbreaks*
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Female
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Germany / epidemiology
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Humans
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Immunity / immunology
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Incidence
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Male
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Middle Aged
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Pertussis Vaccine / immunology
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Risk Factors
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Schools*
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Vaccination / statistics & numerical data
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Whooping Cough / epidemiology*
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Whooping Cough / immunology*
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Whooping Cough / microbiology
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Whooping Cough / transmission
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Young Adult
Substances
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Antibodies, Bacterial
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Pertussis Vaccine