From theoretical synergy to clinical supra-additive toxicity

MeSH terms

• Angiogenesis Inhibitors / administration & dosage
• Angiogenesis Inhibitors / adverse effects
• Antibodies, Monoclonal / administration & dosage
• Antibodies, Monoclonal / adverse effects
• Antibodies, Monoclonal, Humanized
• Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
• Antineoplastic Combined Chemotherapy Protocols / adverse effects*
• Bevacizumab
• Carcinoma, Renal Cell / blood supply
• Carcinoma, Renal Cell / drug therapy*
• Drug Synergism
• Humans
• Hypertension / chemically induced
• Indoles / administration & dosage
• Indoles / adverse effects
• Kidney Neoplasms / blood supply
• Kidney Neoplasms / drug therapy*
• Neovascularization, Pathologic / drug therapy
• Neovascularization, Pathologic / metabolism
• Pyrroles / administration & dosage
• Pyrroles / adverse effects
• Sunitinib
• Vascular Endothelial Growth Factor A / antagonists & inhibitors
• Vascular Endothelial Growth Factor A / metabolism