Integrating sequence, evolution and functional genomics in regulatory genomics

Martin Vingron; Alvis Brazma; Richard Coulson; Jacques van Helden; Thomas Manke; Kimmo Palin; Olivier Sand; Esko Ukkonen

doi:10.1186/gb-2009-10-1-202

Integrating sequence, evolution and functional genomics in regulatory genomics

Genome Biol. 2009;10(1):202. doi: 10.1186/gb-2009-10-1-202. Epub 2009 Jan 30.

Authors

Martin Vingron¹, Alvis Brazma, Richard Coulson, Jacques van Helden, Thomas Manke, Kimmo Palin, Olivier Sand, Esko Ukkonen

Affiliation

¹ Computational Molecular Biology, Max-Planck-Institut für molekulare Genetik, Berlin, Germany. [email protected]

Abstract

With genome analysis expanding from the study of genes to the study of gene regulation, 'regulatory genomics' utilizes sequence information, evolution and functional genomics measurements to unravel how regulatory information is encoded in the genome.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Base Sequence
Computational Biology / methods
Databases, Nucleic Acid
Evolution, Molecular
Genomics / methods*
Regulatory Elements, Transcriptional / genetics*