The treatment of postmenopausal osteoporosis has been thoroughly studied in recent years, because of the large diffusion of this condition. The therapeutic use of synthetic calcitonin from salmon, associated with oral calcium, has been successfully performed in 18 women out of 20, aged 55-65 years old, all suffering from postmenopausal osteoporosis without bone fractures. The dose used (100 MRC), the type of administration, and the duration of treatment (1 injection i.m. daily, for 30 days, and 1 every other day, for the next 60 days), can be taken as a useful therapeutical scheme, also by the general practitioner.