Paget-Schroetter syndrome forerunning the diagnoses of thoracic outlet syndrome and thrombophilia

Clin Appl Thromb Hemost. 2010 Jun;16(3):351-5. doi: 10.1177/1076029609332109. Epub 2009 Feb 25.

Abstract

Reported here is a 22-year-old professional wrestler who was diagnosed to have Paget-Schroetter syndrome after Greco-Roman wrestling. On substantial neuromuscular examination and laboratory testing, he was found to have also thoracic outlet syndrome and heterozygous mutations for factor V Leiden and methyltetrahydrofolate reductase genes. To the best knowledge of the authors, the concomitance of these pathologies is discussed for the first time in the literature.

Publication types

  • Case Reports

MeSH terms

  • Activated Protein C Resistance / complications
  • Activated Protein C Resistance / genetics
  • Anticoagulants / therapeutic use
  • Aspirin / therapeutic use
  • Enoxaparin / therapeutic use
  • Factor V / genetics
  • Heterozygote
  • Humans
  • Magnetic Resonance Angiography
  • Male
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Occupational Diseases / etiology
  • Subclavian Vein
  • Thoracic Outlet Syndrome / complications
  • Thoracic Outlet Syndrome / diagnosis*
  • Thrombophilia / complications
  • Thrombophilia / diagnosis*
  • Thrombophilia / genetics
  • Upper Extremity Deep Vein Thrombosis / diagnosis
  • Upper Extremity Deep Vein Thrombosis / etiology*
  • Warfarin / therapeutic use
  • Wrestling / injuries
  • Young Adult

Substances

  • Anticoagulants
  • Enoxaparin
  • factor V Leiden
  • Warfarin
  • Factor V
  • Methylenetetrahydrofolate Reductase (NADPH2)
  • Aspirin