A tumour diagnosed as schwannoma with some unusual features affecting a single farmed seabream is described. The fish had a single mass on its back. The mass had well-defined limits and arose from the subcutis. The skin over the tumour was ulcerated. Histologically, the neoplasia consisted of Antoni Type A tissue forming irregularly dispersed bundles, within which a large number of fat cells was detected. No Antoni Type B tissue was observed. There was immunohistochemical evidence indicating a positive reaction of neoplastic cells tested with S-100 and calretinin. As far as we know, this is the first report of schwannoma in seabream.