Abstract
Mesothelioma is a rare malignancy arising from mesothelial cells lining the pleura and peritoneum. Advances in modern technology have allowed the development of array based approaches to the study of disease allowing researchers the opportunity to study many genes or proteins in a high-throughput fashion. This review describes the current knowledge surrounding array based approaches with respect to mesothelioma research.
MeSH terms
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DNA, Neoplasm / analysis
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Female
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Gene Expression Profiling*
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Gene Expression Regulation, Neoplastic
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Genetic Predisposition to Disease / epidemiology*
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Humans
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Male
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Mesothelioma / genetics*
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Mesothelioma / pathology
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Mesothelioma / therapy
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Microdissection
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Neoplasm Staging
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Oligonucleotide Array Sequence Analysis*
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Pleural Neoplasms / genetics*
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Pleural Neoplasms / pathology
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Pleural Neoplasms / therapy
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Proteomics
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Reproducibility of Results
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Reverse Transcriptase Polymerase Chain Reaction
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Sensitivity and Specificity