This paper uses examples to illustrate the challenges to health and law professionals interested in public health interventions to reduce the negative impact of companies making money by selling products that put children and young people at risk. Examples included are folate to prevent neural tube defects, with issues around the food industry attempting to block mandatory fortification of flour with folate; fetal alcohol syndrome and hazardous drinking in young people, with a focus on the actions of the alcohol industry including vendors; smoking and the ways in which the tobacco industry still target children; and childhood obesity, with problems again from the food and drink industries including vendors.