Gynaecological uses of a new class of steroids: the selective progesterone receptor modulators

Gynecol Endocrinol. 2009 Feb;25(2):67-73. doi: 10.1080/09513590802531120.

Abstract

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo. This review evaluates the actual and potential usefulness of SPRMs in gynaecology.

Publication types

  • Editorial

MeSH terms

  • Abortion, Induced
  • Contraception
  • Female
  • Humans
  • Pregnancy
  • Receptors, Progesterone / agonists*
  • Receptors, Progesterone / antagonists & inhibitors*
  • Steroids / therapeutic use*
  • Uterine Diseases / drug therapy*

Substances

  • Receptors, Progesterone
  • Steroids