[Prevalence and predictors of masked inefficacy of treatment of arterial hypertension during use of various groups of antihypertensive drugs]

Kardiologiia. 2009;49(2):32-7.
[Article in Russian]

Abstract

Prevalence and predictors of masked arterial hypertension (AH) in patients receiving antihypertensive therapy (concealed treatment inefficacy--CTI) was studied on material of data base comprising 219 observations. Drugs from 5 groups were used. Prevalence of CTI AH with the use of various definitions was 8.1-17.4%. With the help of procedure of logistic regression analysis the following predictors of CTI were selected: (1) sociopsychological--high working capacity, high psychological abilities and social self feeling; (2) parameters of 24-hour BP profile--24-hour variability, variability during working period, minimal daytime BP level, time of maximal BP. According to our data CTI is most probable during treatment with calcium antagonists and beta-adrenoblockers.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adult
  • Antihypertensive Agents / therapeutic use*
  • Blood Pressure / physiology*
  • Blood Pressure Monitoring, Ambulatory
  • Female
  • Humans
  • Hypertension / drug therapy
  • Hypertension / epidemiology*
  • Hypertension / physiopathology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Russia / epidemiology
  • Treatment Outcome

Substances

  • Antihypertensive Agents