[Necrosis of the glans penis: a complication of an injection of buprenorphin in a opioid abuser]

E Hornez; J Laroche; T Monchal; S Bourgouin; P Riviere; R Fournier; E Dantzer

doi:10.1016/j.anplas.2008.12.004

[Necrosis of the glans penis: a complication of an injection of buprenorphin in a opioid abuser]

Ann Chir Plast Esthet. 2010 Apr;55(2):159-61. doi: 10.1016/j.anplas.2008.12.004. Epub 2009 Mar 9.

[Article in French]

Authors

E Hornez¹, J Laroche, T Monchal, S Bourgouin, P Riviere, R Fournier, E Dantzer

Affiliation

¹ Service de chirurgie viscérale et vasculaire, hôpital d'instruction-des-Armées Sainte-Anne, boulevard Sainte-Anne, 83000 Toulon, France. [email protected]

PMID: 19269730
DOI: 10.1016/j.anplas.2008.12.004

Abstract

Necrosis of the penis glans is commonly described after circumcision or strangulation. We report the case of a patient, opioid abuser, who presented an isolated glans necrosis after an injection of buprenorphin. The buprenorphin (Subutex) is a sublingual partial mu-opioid agonist used for the treatment of heroin dependance. Its intravenous or subcutaneous abuse is associated with local infection. The patient require a surgical intervention. After the failure of a mucosal graft, a soft skin graft was done.

Publication types

Case Reports
English Abstract

MeSH terms

Adult
Buprenorphine / administration & dosage
Buprenorphine / adverse effects*
Cocaine-Related Disorders* / rehabilitation
Follow-Up Studies
Heroin Dependence* / rehabilitation
Humans
Injections, Subcutaneous
Male
Narcotic Antagonists / administration & dosage
Narcotic Antagonists / adverse effects*
Necrosis
Penis / drug effects*
Penis / surgery
Reoperation
Skin Transplantation
Surgical Wound Infection / etiology
Surgical Wound Infection / surgery
Wound Healing / physiology

Substances

Narcotic Antagonists
Buprenorphine